• Causal modelling of variation in clinical practice and long-term outcomes of ADHD using Norwegian registry data: The ADHD controversy project 

      Mykletun, Arnstein; Widding-Havneraas, Tarjei; Chaulagain, Ashmita; Lyhmann, Ingvild; Bjelland, Ingvar; Halmøy, Anne; Elwert, Felix; Butterworth, Peter; Markussen, Simen; Zachrisson, Henrik Daae; Rypdal, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-19)
      <p><i>Introduction:</i> Attention-deficit/hyperactivity disorder (ADHD) is among the most common mental disorders in children and adolescents, and it is a strong risk factor for several adverse psychosocial outcomes over the lifespan. There are large between-country and within-country variations in diagnosis and medication rates. Due to ethical and practical considerations, a few studies have examined ...
    • Effect of ADHD medication on risk of injuries: a preference-based instrumental variable analysis 

      Widding-Havnerås, Tarjei; Elwert, Felix; Markussen, Simen; Zachrisson, Henrik Daae; Lyhmann, Ingvild; Chaulagain, Ashmita; Bjelland, Ingvar; Halmøy, Anne; Rypdal, Knut; Mykletun, Arnstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-24)
      ADHD is associated with an increased risk of injury. Causal evidence for efects of pharmacological treatment on injuries is scarce. We estimated efects of ADHD medication on injuries using variation in provider preference as an instrumental variable (IV). Using Norwegian registry data, we followed 8051 patients who were diagnosed with ADHD aged 5 to 18 between 2009 and 2011 and recorded their ADHD ...
    • Effect of Pharmacological Treatment of Attention-Deficit/Hyperactivity Disorder on Criminality 

      Widding-Havnerås, Tarjei; Zachrisson, Henrik Daae; Markussen, Simen; Elwert, Felix; Lyhmann, Ingvild; Chaulagain, Ashmita; Bjelland, Ingvar; Halmøy, Anne; Rypdal, Knut; Mykletun, Arnstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-27)
      Objective: Criminality rates are higher among persons with attention-deficit/hyperactivity disorder (ADHD), and evidence that medication reduces crime is limited. Medication rates between clinics vary widely even within universal health care systems, partly because of providers’ treatment preferences. We used this variation to estimate causal effects of pharmacological treatment of ADHD on 4-year ...
    • Geographical variation in ADHD: do diagnoses refect symptom levels? 

      Widding-Havneraas, Tarjei; Markussen, Simen; Elwert, Felix; Lyhmann, Ingvild; Bjelland, Ingvar; Halmøy, Anne; Chaulagain, Ashmita; Ystrøm, Eivind; Mykletun, Arnstein; Zachrisson, Henrik Daae (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-18)
      Rates of ADHD diagnosis vary across regions in many countries. However, no prior study has investigated how much within-country geographic variation in ADHD diagnoses is explained by variation in ADHD symptom levels. We examine whether ADHD symptom levels explain variation in ADHD diagnoses among children and adolescents using nationwide survey and register data in Norway. Geographical variation in ...
    • Preference-based instrumental variables in health research rely on important and underreported assumptions: a systematic review 

      Widding-Havneraas, Tarjei; Chaulagain, Ashmita; Lyhmann, Ingvild; Zachrisson, Henrik Daae; Elwert, Felix; Markussen, Simen; McDaid, David; Mykletun, Arnstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-11)
      <i>Objective</i> - Preference-based instrumental variables (PP IV) designs can identify causal effects when patients receive treatment due to variation in providers’ treatment preference. We offer a systematic review and methodological assessment of PP IV applications in health research.<br><br> <i>Study Design and Setting</i> - We included studies that applied PP IV for evaluation of any treatment ...